Forward Tim Duncan scored 19 points while pulling down nine rebounds in just 24 minutes. Reserve guard Marco Belinelli had 19 points in 26 minutes. The Spurs were without starting point guard Tony Parker (ankle sprain), but it didn't slow them Friday.
The Spurs (14-2) had their 11-game winning streak snapped Wednesday in Oklahoma City, but they responded by quickly by starting another one, putting the Magic away early.
The Spurs made all 17 of their free throws and hit 42 of 76 shots, 55.3 percent from the field. They made eight of 17 from 3-point range.
The Spurs took an 81-70 lead into the fourth after getting seven points in the third from Ginobili. They opened the fourth by scoring the first 12 points, including back-to-back 3-pointers by Belinelli, to seal the victory.
The hot-shooting Spurs led 63-45 at halftime, hitting 25 of their 41 shots (61 percent) before intermission.
Duncan hit his first four shots, getting eight points in the first eight minutes. He had 17 points and seven rebounds at halftime. He missed only two of his first 10 shots. Forward Kawhi Leonard hit five of his six shots in the first half.
Center Nikola Vucevic, who made his first eight shots in Wednesday's victory, missed his first five shots Friday with Duncan mostly guarding him.
NOTES: Both teams played without their starting point guard. Spurs G Tony Parker missed his first game of the season with an ankle sprain, although he participated in pregame warm-ups and played 34 minutes Wednesday night in Oklahoma City. G Cory Joseph replaced him in the lineup. ... The Magic were without G Jameer Nelson, who played only 12 minutes Wednesday before leaving with a sprained foot. ... G E'Twaun Moore made his first start of the season for the Magic, playing alongside rookie G Victor Oladipo. ... The Spurs allowed only one team (Portland) this season to score 100 points against them. ... Spurs Coach Gregg Popovich didn't sound impressed before the game with his team's faster-than-expected start. The Spurs were 13-1 before losing in Oklahoma City on Wednesday night. "We have a chance to be a better team than we were last year, but we've got a ways to go," he said before tipoff. "We've got a lot of wins, but we haven't played a very good schedule. We've got an experienced team, so it might be easier for us to get off to a quicker start than some other teams. I don't think it's odd that we would look decent from the beginning." ... Magic coach Jacque Vaughn both played for Popovich and worked for him as an assistant coach in San Antonio.