The Terriers (7-5) were able to come back from a halftime deficit behind Cannon, who is from Allentown, Pa., just a few miles from the Lafayette campus.
Trist scored with 2:00 left to pull Lafayette, which trailed by 11 with 8:05 to go, to within 62-58. After a St. Francis Brooklyn turnover, Trist made a free throw with 1:02 left to make it 62-59. Scott hit a 3-pointer to tie the score at 62 with 21 seconds left before Isailovic (nine points) hit the winning shot.
The Leopards led 34-30 at halftime, but the Terriers scored the first nine points of the second half to take a 39-30 lead. Lafayette finally got on the board to make it 39-32, but St. Francis Brooklyn made it 48-38 on a 3-pointer by Isailovic.
The Leopards were playing for the second time in three days, following a 79-54 win over Immaculata on Tuesday. Scott (ankle) did not play against Immaculata. The Leopards are off until a game at Seton Hall on Dec. 27.